Mertansine

Overview

Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery. Mertansine can be attached to a monoclonal antibody with a linker to create an antibody-drug conjugate (ADC).

Application

Products | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Cytoskeleton | Products > Signaling Pathways > Antibody-Drug Conjugate/ADC Related | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Signaling Pathways > Microtubule/Tubulin | Products > Signaling Pathways > ADC Payloads

Product Information

• Catalog No.: HY-19792
• CAS No.: 139504-50-0
• Molecular Formula: C35H48ClN3O10S
• Molecular Weight: 738.29
• Purity: 99.75%
• Storage: Powder -20°C, 3 years , 4°C, 2 years * The compound is unstable in solutions, freshly prepared is recommended.
• Solubility: 0.83 mg/mL (1.12 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source