JNJ-63533054

Overview

JNJ-63533054 is a potent, selective and orally active GPR139 agonist with an EC 50 of 16 nM for human GPR139 (hGPR139) . JNJ-63533054 shows selective for GPR139 over other GPCRs, ion channels, and transporters. JNJ-63533054 can cross the blood-brain barrier (BBB).

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > GPR139

Product Information

• Catalog No.: HY-19838
• CAS No.: 1802326-66-4
• Molecular Formula: C17H17ClN2O2
• Molecular Weight: 316.78
• Purity: 99.80%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (7.89 mM); Clear solution
• Availability: In-stock

Source

Original product source