MK-0941

Overview

MK-0941 is a selective, orally active, and allosteric glucokinase activator with EC 50 s of 240 and 65 nM for recombinant human glucokinase in the presence of 2.5 and 10 mM glucose, respectively. MK-0941 activates hexokinase subtype IV . MK-0941 can increase insulin secretion and glucose uptake. MK-0941 can be studied in research for type 2 diabetes.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Glucose Metabolism | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Glucokinase

Product Information

• Catalog No.: HY-19843
• CAS No.: 1137916-97-2
• Molecular Formula: C22H28N4O9S2
• Molecular Weight: 556.61
• Purity: 99.38%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.17 mg/mL (3.90 mM); Clear solution
• Availability: In-stock

Source

Original product source