VRX-480773 is an efficient non-nucleoside reverse transcriptase inhibitor ( NNRTI ), used for HIV infection . VRX-480773 has high specificity for HIV-1 , with an EC 50 for wild-type HIV-1 being 0.14 nM. VRX-480773 does not inhibit HIV-2 , HBV or HCV , and has no effect on human DNA polymerase α/β. VRX-480773 retains inhibitory activity against Efavirenz ( HY-10572 ) resistant strains, with EC 50 s mostly < 1 nM. VRX-480773 can be used for research on AIDS.
Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > HIV | Products > Signaling Pathways > Reverse Transcriptase
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