(R)-BMS-816336 (Compound 6n-1) is a potent and orally active inhibitor of human , mouse and cynomolgus monkey 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) enzyme with IC 50 s of 14.5 nM, 50.3 nM and 16 nM, respectively .
Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > 11β-HSD
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