hVEGF-IN-1 (Standard) is the analytical standard of hVEGF-IN-1 ( HY-101931 ). This product is intended for research and analytical applications. hVEGF-IN-1 , a quinazoline derivative, could specifically bind to the G-rich sequence in the internal ribosome entry site A (IRES-A) and destabilize the G-quadruplex structure. hVEGF-IN-1 binds to the IRES-A (WT) with a K d of 0.928 μM in SPR experiments. hVEGF-IN-1 could hinder tumor cells migration and repress tumor growth by decreasing VEGF-A protein expression.
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