Vactosertib Hydrochloride

Overview

Vactosertib Hydrochloride (EW-7197 Hydrochloride) is a potent, orally active and ATP-competitive activin receptor-like kinase 5 ( ALK5 ) inhibitor with an IC 50 of 12.9 nM. Vactosertib Hydrochloride also inhibits ALK2 and ALK4 ( IC 50 of 17.3 nM) at nanomolar concentrations. Vactosertib Hydrochloride has potently antimetastatic activity and anticancer effect.

Application

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Product Information

• Catalog No.: HY-19928A
• CAS No.: 1352610-25-3
• Molecular Formula: C22H19ClFN7
• Molecular Weight: 435.88
• Purity: 99.22%
• Storage: -20°C, stored under nitrogen, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
• Solubility: ≥ 2.5 mg/mL (5.74 mM); Clear solution
• Availability: In-stock

Source

Original product source