MK-2748

Overview

MK-2748 is a hepatitis C virus ( HCV ) NS3/4a protease inhibitor. MK-2748 exhibits broad-spectrum and potent antiviral activity, with nanomolar-level activity against all genotypes (gt1a-gt6) ( IC₅₀ < 0.115 nM), showing only slightly weaker activity against gt3a (1.212 nM), and maintaining high inhibitory activity against drug-resistant mutant strains such as gt1b R155K ( IC₅₀ = 0.032 nM) and D168Y ( IC₅₀ = 0.057 nM). MK-2748 can be used in the research of HCV infection .

Application

Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Infection | Products > Signaling Pathways > HCV Protease | Products > Signaling Pathways > HCV

Product Information

• Catalog No.: HY-19932
• CAS No.: 1193902-95-2
• Molecular Formula: C42H56N6O10S
• Molecular Weight: 836.99
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source