(3S,4S)-PF-06459988

Overview

(3S, 4S)-PF-06459988 is the S enantiomer of PF-06459988 with less active. PF-06459988 is a potent irreversible inhibitor of T790M mutant epidermal growth factor receptor ( EGFR ). PF-06459988 has excellent selectivity against EGFR wild-type while possessing a minimally reactive electrophile that reduces the propensity of off-target labeling.

Application

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Product Information

• Catalog No.: HY-19985A
• CAS No.: 1858291-14-1
• Molecular Formula: C19H22ClN7O3
• Molecular Weight: 431.88
• Purity: 98.97%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (5.79 mM); Clear solution
• Availability: In-stock

Source

Original product source