BI-0115

Overview

BI-0115 is a selective inhibitor of LOX-1 ( IC 50 =5.4 μM) that blocks cellular uptake of oxLDL. BI-0115 binding triggers receptor inhibition by formation of dimers of the homodimeric ligand binding domain.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Cardiovascular Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > LOX-1

Product Information

• Catalog No.: HY-23999
• CAS No.: 4929-23-1
• Molecular Formula: C15H14ClN3O
• Molecular Weight: 287.74
• Purity: 99.72%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (8.69 mM); Clear solution
• Availability: In-stock

Source

Original product source