β-Carboline-1-carboxylic acid

Overview

β-Carboline 1-carboxylic acid is a β-carboline alkaloid with anti-inflammatory, antifibrotic, antitumor and antibacterial activities. β-Carboline 1-carboxylic acid is the cAMP phosphodiesterase ( IC 50 : 96 µM) and indoleamine 2, 3-dioxygenase ( IDO ) inhibitor. β-Carboline 1-carboxylic acid is cytotoxic to tumor cells. β-Carboline 1-carboxylic acid inhibits inflammation through the NF-κb/p65 pathway and can reverse epithelial-mesenchymal transition (EMT). In addition, β-Carboline 1-carboxylic acid has strong inhibitory activity against S. aureus ( IC 50 : 47.70 μg/mL) and E. coli ( IC 50 : 19.17 μg/mL).

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > NF-κB | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Infection | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Bacterial | Products > Signaling Pathways > Indoleamine 2,3-Dioxygenase (IDO) | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Phosphodiesterase (PDE)

Product Information

• Catalog No.: HY-29268
• CAS No.: 26052-96-0
• Molecular Formula: C12H8N2O2
• Molecular Weight: 212.20
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source