Eflornithine hydrochloride, hydrate

Overview

Eflornithine hydrochloride, hydrate is a drug found to be effective in the treatment of facial hirsutism. It is a "suicide inhibitor," irreversibly binding to Ornithine Decarboxylase (ODC) and preventing the natural substrate ornithine from accessing the active site. It is an irreversible inhibitor of ornithine decarboxylase that suppresses polyamine biosynthesis. It displays antiangiogenic and cytostatic effects in tumor cells but must be used in combination with other chemotherapeutic agents to negate compensatory increases in polyamine content through alternate synthesis pathways. It also demonstrates antiparasitic activity in a model of C. parvum infection. Source summary: Eflornithine hydrochloride, hydrate serves as a crucial compound for biochemical research into polyamine biosynthetic pathways. Request quotation on our website.

Application

Products > Drug Discovery > Inhibitor > Other Inhibitors | Products > Drug Discovery > Inhibitor

Product Information

• Catalog No.: B0084-080177
• CAS No.: 96020-91-6
• Molecular Formula: C6H15ClF2N2O3
• Molecular Weight: 236.64
• Purity: 98%
• Storage: Store at 2-8 °C
• Solubility: Soluble in Methanol, Water

Source

Original product source