Cot inhibitor-1

Overview

Cot inhibitor-1 (compound 28) is a selective tumor progression loci-2 (Tpl2) kinase inhibitor with an IC 50 of 28 nM. Cot inhibitor-1 shows an inhibition of TNF-alpha production in human whole blood with an IC 50 of 5.7 nM.

Application

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Product Information

• Catalog No.: HY-32015
• CAS No.: 915365-57-0
• Molecular Formula: C27H27Cl2FN8
• Molecular Weight: 553.46
• Purity: 98.45%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (4.52 mM); Clear solution
• Availability: In-stock

Source

Original product source