Ercalcitriol-d 3

Overview

Ercalcitriol -d 3 (1α,25-Dihydroxy Vitamin D2-d 3 ) is the deuterium labeled Ercalcitriol ( HY-32350 ). Ercalcitriol (1α,25-Dihydroxy Vitamin D2) is a vitamin D receptor (VDR) agonist with high binding affinity. After binding to VDR, Ercalcitriol forms a complex with retinoid X receptor (RXR) to regulate target gene transcription. For example, Ercalcitriol induces human gingival/oral epithelial cells to produce human cat antimicrobial peptide (hCAP-18/LL-37), which has antimicrobial activity against periodontal pathogens such as Porphyromonas gingivalis. Ercalcitriol enhances the innate immune defense of the oral mucosa by promoting the expression of antimicrobial peptides, and is mainly used in the study of periodontal diseases and immune-related oral diseases.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Others | Products > Signaling Pathways > Vitamin D Related/Nuclear Receptor | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Isotope-Labeled Compounds | Products > Signaling Pathways > VD/VDR | Products > Signaling Pathways > Endogenous Metabolite

Product Information

• Catalog No.: HY-32350S1
• CAS No.: 1261254-46-9
• Molecular Formula: C28H41D3O3
• Molecular Weight: 431.67
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source