4-Hydroxymethylpyrazole

Overview

4-Hydroxymethylpyrazole is the primary metabolite of Fomepizole ( HY-B0876 ) produced through hepatic oxidative metabolism. 4-Hydroxymethylpyrazole exhibits a plasma concentration that is positively correlated with the administered dosage of Fomepizole , and it demonstrates a relatively short half-life. 4-Hydroxymethylpyrazole demonstrates inhibitory effects on alcohol dehydrogenase ( ADH ) in both humans and monkeys, but its inhibition constant is significantly higher than that of Fomepizole , rendering its in vivo impact negligible.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Drug Metabolite

Product Information

• Catalog No.: HY-33914
• CAS No.: 25222-43-9
• Molecular Formula: C4H6N2O
• Molecular Weight: 98.11
• Purity: 99.74%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (25.48 mM); Clear solution
• Availability: In-stock

Source

Original product source