(R)-AZ8838 is a competitive PAR2 antagonist with a pK i of 5.2 for human PAR2 . (R)-AZ8838 exert anti-inflammatory effects in a rat model of PAR2 agonist-induced paw oedema.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Protease Activated Receptor (PAR)
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