Tomaymycin DM

Overview

Tomaymycin DM is a derivative of Tomaymycin (HY-N10174) that belongs to the class of DNA alkylation inhibitors and acts as an effective payload for ADCs. Tomaymycin stabilizes the double-stranded DNA structure, inhibits various DNA processing enzymes, blocks transcription, and ultimately induces DNA strand breaks and apoptosis. Tomaymycin DM can be used in studies related to the development of ADCs targeting multiple cancers including leukemia and ovarian cancer. - Mechanism of Action & Protocol.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Antibody-Drug Conjugate/ADC Related | Products > Signaling Pathways > Others | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Signaling Pathways > ADC Payloads | Products > Signaling Pathways > Drug Derivative

Product Information

• Catalog No.: HY-102001
• CAS No.: 945490-09-5
• Molecular Formula: C14H14N2O3
• Molecular Weight: 258.27
• Purity: 95.73%
• Storage: -20°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Availability: In-stock

Source

Original product source