Mavorixafor

Overview

Mavorixafor (AMD-070) is a potent, selective and orally available CXCR4 antagonist, with an IC 50 value of 13 nM against CXCR4 125 I-SDF binding, and also inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs with an IC 50 of 1 and 9 nM, respectively. Mavorixafor can be used for the study of WHIM syndrome.

Application

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Product Information

• Catalog No.: HY-50101
• CAS No.: 558447-26-0
• Molecular Formula: C21H27N5
• Molecular Weight: 349.47
• Purity: 99.66%
• Storage: 4°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Solubility: ≥ 2.5 mg/mL (7.15 mM); Clear solution
• Availability: In-stock

Source

Original product source