DGAT-1 inhibitor 2

Overview

DGAT-1 inhibitor 2 is an orally active DGAT-1 inhibitor with IC 50 values of 15 nM and 9 nM for human DGAT-1 and rat DGAT-1, respectively. DGAT-1 inhibitor 2 increases ROS concentration, GRP78 , and PERK protein abundance. DGAT-1 inhibitor 2 increases SREBF1 , CPT1A , and MTTP mRNA in fatty acid-treated cells. DGAT-1 inhibitor 2 improves obesity.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Lipid Metabolism | Products > Disease Areas > Obesity | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > PERK | Products > Signaling Pathways > Carnitine Palmitoyltransferase (CPT) | Products > Signaling Pathways > Acyltransferase | Products > Signaling Pathways > Reactive Oxygen Species (ROS) | Products > Signaling Pathways > HSP

Product Information

• Catalog No.: HY-50670
• CAS No.: 942999-61-3
• Molecular Formula: C24H28N4O3
• Molecular Weight: 420.50
• Purity: 95.33%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: 2.5 mg/mL (5.95 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source