Fiacitabine

Overview

Fiacitabine (NSC 382097; FIAC; FOAC) is a potent and highly selective anti-herpesvirus agent. Fiacitabine acts as an inhibitor of HSV DNA polymerase , with a K i of 0.26 μM for HSV-1 and 0.42 μM for HSV-2 , respectively. Fiacitabine can be efficiently phosphorylated by thymidine kinase encoded by the virus itself to generate FIACTP, an active triphosphate metabolite. Fiacitabine is applicable to research related to herpesvirus infections.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Viral Infection | Products > Disease Areas > HSV Infection | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Infection | Products > Signaling Pathways > HSV | Products > Signaling Pathways > EBV | Products > Signaling Pathways > DNA/RNA Synthesis

Product Information

• Catalog No.: HY-50735
• CAS No.: 69123-90-6
• Molecular Formula: C9H11FIN3O4
• Molecular Weight: 371.10
• Purity: 99.27%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Availability: In-stock

Source

Original product source