Bafetinib (Standard)

Overview

Bafetinib (Standard) is the analytical standard of Bafetinib. This product is intended for research and analytical applications. Bafetinib is an orally active Lyn/Bcr-Abl tyrosine kinase inhibitor. Bafetinib enhances the activity of several pro-apoptotic Bcl-2 homology (BH) 3-pure proteins ( Bim , Bad, Bmf, and Bik) through intrinsic apoptotic pathways regulated by the Bcl-2 family , and induces apoptosis of Ph+ leukemia cells. Bafetinib has antitumor activity.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Others | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Bcr-Abl | Products > Signaling Pathways > Src | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Reference Standards

Product Information

• Catalog No.: HY-50868R
• CAS No.: 859212-16-1
• Molecular Formula: C30H31F3N8O
• Molecular Weight: 576.62
• Purity: 98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source