L-873724

Overview

L-873724 is a potent, orally bioavailable, selective and reversible non-basic cathepsin K inhibitor , with IC 50 s of 0.2, 178, 264, and 5239 nM for cathepsin K , cathepsin S , cathepsin L , cathepsin B , respectively. L-873724 also exhibits an IC 50 of 0.5 nM for rabbit cathepsin K . L-873724 inhibits bone resorption.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Cathepsin

Product Information

• Catalog No.: HY-50887
• CAS No.: 603139-12-4
• Molecular Formula: C23H26F3N3O3S
• Molecular Weight: 481.53
• Purity: 98.93%
• Storage: 4°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Solubility: ≥ 2.5 mg/mL (5.19 mM); Clear solution
• Availability: In-stock

Source

Original product source