Gefitinib

Overview

Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC 50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC 50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy and cell apoptosis , which can be used for cancer related research, such as Lung cancer and breast cancer .

Application

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Product Information

• Catalog No.: HY-50895
• CAS No.: 184475-35-2
• Molecular Formula: C22H24ClFN4O3
• Molecular Weight: 446.90
• Purity: 99.99%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 5 mg/mL (11.19 mM); Clear solution
• Availability: In-stock

Source

Original product source