Paclitaxel is a compound with anti-tumor activity extracted from the Pacific yew tree Taxus brevifolia. Paclitaxel is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells. Source summary: Paclitaxel, as an ADC payload, stabilizes microtubules to induce cell cycle arrest, enhancing ADC-based cancer treatment strategies.
Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Neurological Disease | Microtubule/Tubulin
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