OSI-930 (Standard) is the analytical standard of OSI-930 ( HY-10204 ). This product is intended for research and analytical applications. OSI-930 is an orally selective inhibitor of Kit, KDR and CSF-1R ( c-Fms ) with IC 50 s of 80 nM, 9 nM and 15 nM, respectively. OSI-930 also moderately inhibits Flt-1, c-Raf , Lck and low activity against PDGFRα/β, Flt-3 and Abl. OSI-930 has antitumor activity.
Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > c-Kit | Products > Signaling Pathways > VEGFR | Products > Signaling Pathways > c-Fms | Products > Signaling Pathways > Apoptosis
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