DCEBIO

Overview

DCEBIO is a small/medium conductance calcium-activated potassium (SK Ca /IK Ca ) channel opener and primary neuron signal blocker. It hyperpolarizes the membrane potential of C2C12 myoblasts by activating IK Ca channels, thereby promoting myogenic differentiation. The specific biological activity of DCEBIO is manifested in increased myotube formation, enhanced myosin heavy chain II protein levels and myogenin mRNA levels. DCEBIO can be applied in the field of muscle research, especially in muscle-related degenerative diseases such as sarcopenia.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Potassium Channel

Product Information

• Catalog No.: HY-102052
• CAS No.: 60563-36-2
• Molecular Formula: C9H8Cl2N2O
• Molecular Weight: 231.08
• Purity: 99.25%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (10.82 mM); Clear solution
• Availability: In-stock

Source

Original product source