7-Nitroindazole

Overview

7-Nitroindazole is a selective and BBB-penetrable inhibitor of nitric oxide synthase ( NOS ) ( IC 50 = 0.47 μM in mouse cerebellum). 7-Nitroindazole does not affect blood pressure or endothelium-dependent relaxation while inhibiting nNOS in experimental animals . 7-Nitroindazole has anti-injurious and neuroprotective properties, and can be studied in research for neurological diseases such as Parkinson’s disease.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Neurological Disease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > NO Synthase

Product Information

• Catalog No.: HY-69019
• CAS No.: 2942-42-9
• Molecular Formula: C7H5N3O2
• Molecular Weight: 163.14
• Purity: 99.09%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (15.32 mM); Clear solution
• Availability: In-stock

Source

Original product source