Safinamide

Overview

Safinamide is a potent, selective, and reversible monoamine oxidase B ( MAO-B ) inhibitor ( IC 50 =0.098 μM) over MAO-A (IC 50 =580 μM). Safinamide also blocks sodium channels and modulates glutamate (Glu) release, showing a greater affinity at depolarized ( IC 50 =8 μM) than at resting ( IC 50 =262 μM) potentials. Safinamide has neuroprotective and neurorescuing effects and can be used for the study of parkinson disease, ischemia stroke etc.al.

Application

Products | Products > Disease Areas > Parkinson's Disease | Products > Disease Areas > Infection | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Coronavirus Infection | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Depression | Products > Disease Areas > SARS-CoV-2 Infection | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Monoamine Oxidase

Product Information

• Catalog No.: HY-70057
• CAS No.: 133865-89-1
• Molecular Formula: C17H19FN2O2
• Molecular Weight: 302.34
• Purity: 99.86%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (8.27 mM); Clear solution
• Availability: In-stock

Source

Original product source