Safinamide mesylate

Overview

Safinamide (FCE 26743; EMD 1195686) mesylate is a potent, selective, and reversible monoamine oxidase B ( MAO-B ) inhibitor ( IC 50 =0.098 μM) over MAO-A (IC 50 =580 nM). Safinamide mesylate also blocks sodium channels and modulates glutamate (Glu) release, showing a greater affinity at depolarized ( IC 50 =8 μM) than at resting ( IC 50 =262 μM) potentials. Safinamide mesylate has neuroprotective and neurorescuing effects and can be used for the study of parkinson disease, ischemia stroke et.al.

Application

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Product Information

• Catalog No.: HY-70057A
• CAS No.: 202825-46-5
• Molecular Formula: C18H23FN2O5S
• Molecular Weight: 398.45
• Purity: 99.07%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.08 mg/mL (5.22 mM); Clear solution
• Availability: In-stock

Source

Original product source