SRI-31255

Overview

SRI-31255 is an orally active LRRK2 inhibitor with IC 50 values of 520 and 427 nM for human wild-type (WT) and mutant G2019S, respectively. SRI-31255 exerts neuroprotective effects by binding to the ATP-binding pocket of LRRK2 , inhibiting kinase activity. SRI-31255 can be used as a lead compound for the development of LRRK2-targeted drugs for the treatment of Parkinson's disease.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Autophagy | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > LRRK2

Product Information

• Catalog No.: HY-75368
• CAS No.: 905580-86-1
• Molecular Formula: C15H14N4
• Molecular Weight: 250.30
• Purity: 99.88%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source