MSX3

Overview

MSX3 is an orally active, selective A 2 a adenosine receptor antagonist and a prodrug of MSX2 ( HY-117184 ). MSX3 reduces hyperphosphorylation of Tau at specific epitopes in mice without altering total Tau levels, Tau fragments, or Tau aggregation in these animals . MSX3 enhances spatial memory. MSX3 regulates effort-related decision-making behaviors. MSX3 reverses D 2 antagonist-induced suppression of lever pressing, increased Chow feed intake, reduced selection of high-barrier arms, and prolonged response latency, and also slightly attenuates effects induced by D 1 antagonists. MSX3 can be used in the research of Tauopathies (Alzheimer's disease-related), depression, and Parkinsonism.

Application

Products | Products > Disease Areas > Parkinson's Disease | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Depression | Products > Disease Areas > Alzheimer's Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Adenosine Receptor | Products > Signaling Pathways > Tau Protein

Product Information

• Catalog No.: HY-102086
• CAS No.: 261717-23-1
• Molecular Formula: C21H21N4Na2O7P
• Molecular Weight: 518.37
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source