MMAF intermediate 1 is an intermediate in the synthesis of MMAF ( HY-15579 ). MMAF (Monomethylauristatin F) is a potent inhibitor of tubulin polymerization and the cytotoxic ( ADC Cytotoxin ) component of classic antibody drug conjugates (ADCs), such as Vorsetuzumab mafodotin and SGN-CD19A.
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