MMAF-OMe

MMAF-OMe
  • CAS No.:863971-12-4
  • Grade:96.05%
  • Formula:C40H67N5O8
  • M.W.:745.99
  • Solvent:≥ 2.5 mg/mL (3.35 mM); Clear solution

Overview

MMAF-Ome, an antitubulin agent, is also an ADC cytotoxin . MMAF-Ome inhibits several tumor cell lines with IC 50 s of 0.056 nM, 0.166 nM, 0.183 nM, and 0.449 nM for MDAMB435/5T4, MDAMB361DYT2, MDAMB468, and Raji (5T4 - ) cell lines, respectively.

Application

Products | Products > Signaling Pathways > Antibody-Drug Conjugate/ADC Related | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > ADC Payloads

Product Information

  • Catalog No.: HY-79256
  • CAS No.: 863971-12-4
  • Molecular Formula: C40H67N5O8
  • Molecular Weight: 745.99
  • Purity: 96.05%
  • Storage: Powder -20°C, 3 years , 4°C, 2 years * The compound is unstable in solutions, freshly prepared is recommended.
  • Solubility: ≥ 2.5 mg/mL (3.35 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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