SNX-2112 (Standard)

Overview

SNX-2112 (Standard) is the analytical standard of SNX-2112 ( HY-10214 ). This product is intended for research and analytical applications. SNX-2112 (PF 04928473) is an orally active Hsp90 inhibitor , with a K d of 16 nM for Hsp90 and IC 50 s of 30 nM, 30 nM for Hsp90 α and Hsp90 β, also induces Her-2 degradation, and inhibits Grp94 and Trap-1, with IC 50 s of 10 nM, 4.275 μM and 0.862 μM, respectively. SNX-2112 (PF 04928473) binds Hsp90 isoforms Hsp90α, Hsp90β and Hsp90b1/Grp94 with Kds of 4 nM, 6 nM and 484 nM, respectively.

Application

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Product Information

• Catalog No.: HY-10214R
• CAS No.: 908112-43-6
• Molecular Formula: C23H27F3N4O3
• Molecular Weight: 464.48
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source