Tianeptine

Overview

Tianeptine is an atypical antidepressant. Tianeptine is a moderate-intensity agonist of the μ-opioid receptor ( MOR ), and to a lesser extent, is an agonist of the δ-opioid receptor ( DOR ). Tianeptine is a glutamate modulator that can enhance AMPA receptor and antagonize NMDA receptor . tianeptine increases sensitivity of the α1 adrenergic receptor , which only manifests in chronic treatment. Tianeptine exerts neuroprotective effects under stress/inflammation-induced conditions, exhibiting anti-inflammatory and antioxidant properties. Tianeptine inhibits MMP-9 by suppressing the PI3K/Akt -mediated NF-κB pathway. Tianeptine can be used to alleviate symptoms of depression and anxiety, but does not cause sedative effects.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > NF-κB | Products > Research Areas > Neurological Disease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > MMP | Products > Signaling Pathways > PI3K | Products > Signaling Pathways > Akt | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Opioid Receptor | Products > Signaling Pathways > iGluR

Product Information

• Catalog No.: HY-90003
• CAS No.: 72797-41-2
• Molecular Formula: C21H25ClN2O4S
• Molecular Weight: 436.95
• Purity: 99.21%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 1 mg/mL (2.29 mM); Clear solution
• Availability: In-stock

Source

Original product source