Dronedarone

Overview

Dronedarone (SR 33589), a derivative of amiodarone ( HY-14187 ), is a class III antiarrhythmic agent for the study of atrial fibrillation (AF) and atrial flutter. Dronedarone is a potent blocker of multiple ion currents , including potassium current, sodium current, and L-type calcium current, and exhibits antiadrenergic effects by noncompetitive binding to β-adrenergic receptors. Dronedarone is a substrate for and a moderate inhibitor of CYP3A4 .

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Cardiovascular Disease | Products > Disease Areas > Heart Disease | Products > Disease Areas > Hypertension | Products > Disease Areas > Atrial Fibrillation | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Autophagy | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Adrenergic Receptor | Products > Signaling Pathways > Cytochrome P450 | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > mAChR | Products > Signaling Pathways > Sodium Channel | Products > Signaling Pathways > Calcium Channel

Product Information

• Catalog No.: HY-A0016
• CAS No.: 141626-36-0
• Molecular Formula: C31H44N2O5S
• Molecular Weight: 556.76
• Purity: 99.93%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (4.49 mM); Clear solution
• Availability: In-stock

Source

Original product source