Rapamycin (GMP Like)

Overview

Rapamycin (Sirolimus) GMP Like is Rapamycin ( HY-10219 ) produced by using GMP like guidelines. GMP Like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Rapamycin (Sirolimus; AY 22989) is a potent and specific blood-brain barrier-transmissible mTOR inhibitor with an IC 50 of 0.1 nM in HEK293 cells. Rapamycin is a molecular glue that binds FKBP12 and mTOR proteins together, thereby inhibiting mTOR kinase activity. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1 . Rapamycin is an autophagy activator, an immunosuppressant.

Application

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Product Information

• Catalog No.: HY-10219GL
• CAS No.: 53123-88-9
• Molecular Formula: C51H79NO13
• Molecular Weight: 914.17
• Purity: 98.8%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source