Fluphenazine dihydrochloride

Overview

Fluphenazine dihydrochloride is a potent, orally active phenothiazine-based dopamine receptor antagonist. Fluphenazine dihydrochloride blocks neuronal voltage-gated sodium channels . Fluphenazine dihydrochloride acts primarily through antagonism of postsynaptic dopamine-2 receptors in mesolimbic, nigrostriatal, and tuberoinfundibular neural pathways. Fluphenazine dihydrochloride can antagonize Methylphenidate-induced stereotyped gnawing and inhibit climbing behaviour in mice. Fluphenazine dihydrochloride can be used for researching psychosis and painful peripheral neuropathy associated with diabetes and has potential to inhibit SARS-CoV-2 .

Application

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Product Information

• Catalog No.: HY-A0081
• CAS No.: 146-56-5
• Molecular Formula: C22H28Cl2F3N3OS
• Molecular Weight: 510.44
• Purity: 99.91%
• Storage: -20°C, stored under nitrogen, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
• Solubility: ≥ 2.08 mg/mL (4.07 mM); Clear solution
• Availability: In-stock

Source

Original product source