Halofantrine hydrochloride (Standard)

Halofantrine hydrochloride (Standard)
  • CAS No.:36167-63-2
  • Grade:99.98%
  • Formula:C26H31Cl3F3NO
  • M.W.:536.88

Overview

Halofantrine hydrochloride (Standard) is the analytical standard of Halofantrine hydrochloride. This product is intended for research and analytical applications. Halofantrine hydrochloride (SKF-102886 hydrochloride; WR-171669 hydrochloride) is a blocker that delays the delayed rectifier potassium current by inhibiting human ERG channels, and it is a potent antimalarial agent. Halofantrine hydrochloride inhibits the Cap1 -dependent oxidative stress response of Candida albicans , suppresses ROS responses, and enhances the antifungal ( Fungal ) activity of oxidative damage agents. Halofantrine hydrochloride exhibits antifungal activity in the Galleria mellonella model, and shows antimalarial activity against Plasmodium strains both in vitro and in animal models. Halofantrine hydrochloride can be used in studies related to invasive candidiasis, falciparum malaria, and vivax malaria.

Application

Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Others | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Infection | Products > Signaling Pathways > Fungal | Products > Signaling Pathways > Potassium Channel | Products > Signaling Pathways > Reactive Oxygen Species (ROS) | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > Parasite

Product Information

  • Catalog No.: HY-A0148AR
  • CAS No.: 36167-63-2
  • Molecular Formula: C26H31Cl3F3NO
  • Molecular Weight: 536.88
  • Purity: 99.98%
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source


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