THIP

Overview

THIP (Gaboxadol) is a selective extrasynaptic GABAA receptors ( eGABARs ) agonist (with blood-brain barrier permeability), shows an EC 50 value of 13 μM for δ-GABAAR . THIP induces strong tense GABAA -mediated currents in layer 2/3 neurons, but shows on effect on miniature IPSCs. THIP can be used in studies of sleep disorders.

Application

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Product Information

• Catalog No.: HY-10232
• CAS No.: 64603-91-4
• Molecular Formula: C6H8N2O2
• Molecular Weight: 140.14
• Purity: 99.89%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (17.84 mM); Clear solution
• Availability: In-stock

Source

Original product source