Gaboxadol hydrochloride

Overview

Gaboxadol hydrochloride (Lu 02-030 hydrochloride) is a potent agonist of the GABA A receptor and an antagonist of GABA C receptors ( IC 50 =25 μM). Gaboxadol hydrochloride displays a partial agonist efficacy on subunit α1β2γ2 with an ED 50 value of 143 μM, a full agonist efficacy at α5 subunit ( ED 50 =28-129 μM) and a superagonist efficacy at α4β3δ ( ED 50 =6 μM). Gaboxadol hydrochloride is a non-opioid agent.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Alzheimer's Disease | Products > Disease Areas > Parkinson's Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > GABA Receptor

Product Information

• Catalog No.: HY-10233
• CAS No.: 85118-33-8
• Molecular Formula: C6H9ClN2O2
• Molecular Weight: 176.60
• Purity: 99.90%
• Storage: 4°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Solubility: ≥ 1.47 mg/mL (8.32 mM); Clear solution
• Availability: In-stock

Source

Original product source