Azelastine HCl

Overview

Azelastine HCl is a potent, second-generation, selective, histamine antagonist. It inhibits histamine via competing with histamine for the H1 receptor.

Application

Products > Drug Discovery > Impurities > Immune System > Azelastine and Impurities | Products > Drug Discovery > Inhibitor

Product Information

• Catalog No.: B0084-098591
• CAS No.: 79307-93-0
• Molecular Formula: C22H25Cl2N3O
• Molecular Weight: 418.36
• Purity: >98%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture)
• Solubility: In Vitro : DMSO : 50 mg/mL(119.51 mM;Need ultrasonic) H2O : 6.67 mg/mL(15.94 mM;Need ultrasonic) In Vivo: 1.Add each solvent one by one:10% DMSO >> 40%PEG300 >> 5%Tween-80 >> 45% saline Solubility: ≥ 2.5 mg/mL (5.98 mM); Clear solution 2.Add each solvent one by one:10% DMSO >> 90% (20%SBE-β-CDin saline) Solubility: ≥ 2.5 mg/mL (5.98 mM); Clear solution

Source

Original product source