Docetaxel

Overview

Docetaxel (RP-56976) is a microtubule depolymerization inhibitor, with an IC 50 of 0.2 μM. Docetaxel attenuates the effects of bcl-2 and bcl-xL gene expression. Docetaxel arrests the cell cycle at G2/M and leads to cell apoptosis . Docetaxel has anti-cancer activity.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > Lung Cancer | Products > Disease Areas > Respiratory Cancer | Products > Disease Areas > Breast Cancer | Products > Disease Areas > Prostate Cancer | Products > Disease Areas > Urogenital Cancer | Products > Disease Areas > Pancreatic Cancer | Products > Disease Areas > Digestive System Cancer | Products > Disease Areas > Viral Infection | Products > Disease Areas > Digestive System Inflammation | Products > Disease Areas > Non-Small Cell Lung Cancer | Products > Disease Areas > Lung Adenocarcinoma | Products > Disease Areas > Lung Squamous Cell Carcinoma | Products > Disease Areas > HER-2 Positive Breast Cancer | Products > Disease Areas > Triple-Negative Breast Cancer | Products > Disease Areas > Metastatic Breast Cancer | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Cytoskeleton | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Microtubule/Tubulin | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Endogenous Metabolite

Product Information

• Catalog No.: HY-B0011
• CAS No.: 114977-28-5
• Molecular Formula: C43H53NO14
• Molecular Weight: 807.88
• Purity: 99.94%
• Storage: 4°C, protect from light * In solvent : -80°C, 1 year; -20°C, 6 months (protect from light)
• Solubility: ≥ 5 mg/mL (6.19 mM); Clear solution
• Availability: In-stock

Source

Original product source