Danoprevir (Standard)

Overview

Danoprevir (Standard) is the analytical standard of Danoprevir ( HY-10238 ). This product is intended for research and analytical applications. Danoprevir (ITMN-191) is an orally active NS3/4A protease inhibitor for hepatitis C virus ( HCV ) with an IC 50 of 0.29 nM and is selective for NS3/4A over a panel of 53 proteases (IC 50 higher than 10 μM). Danoprevir (ITMN-191) inhibits HCV genotypes 1a, 1b, 4, 5, and 6 (IC 50 s=0.2-0.4 nM) as well as 2b and 3a (IC 50 s=1.6, 3.5 nM). Danoprevir is also a SARS-CoV 3CLpro inhibitor with an IC 50 of 0.05 μM.

Application

Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Infection | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > HCV Protease | Products > Signaling Pathways > HCV | Products > Signaling Pathways > SARS-CoV

Product Information

• Catalog No.: HY-10238R
• CAS No.: 850876-88-9
• Molecular Formula: C35H46FN5O9S
• Molecular Weight: 731.83
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source