Levoketoconazole

Overview

Levoketoconazole ((-)-Ketoconazole) is the 2S,4R enantiomer derived from racemic Ketoconazole ( HY-B0105 ). Levoketoconazole is a potent and orally active cortisol synthesis inhibitor. Levoketoconazole inhibits key steps in cortisol and testosterone synthesis by inhibiting CYP11B1 , CYP11A1 , and CYP17A1 . Levoketoconazole can be used for research on endogenous Cushing’s syndrome.

Application

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Product Information

• Catalog No.: HY-B0105B
• CAS No.: 142128-57-2
• Molecular Formula: C26H28Cl2N4O4
• Molecular Weight: 531.43
• Purity: 99.82%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (4.70 mM); Clear solution
• Availability: In-stock

Source

Original product source