Omeprazole sulfone (methoxy-d 3 )

Overview

Omeprazole sulfone (methoxy-d 3 ) is the deuterium labeled Omeprazole sulfone. Omeprazole sulfone (H 16868) is an orally active H + ,K + -ATPase inhibitor and a proton pump inhibitor. Omeprazole sulfone competitively inhibits CYP2C19 , CYP3A4 , and CYP2C9 activity. Omeprazole sulfone inhibits gastric acid secretion and can be used for acid-related gastrointestinal disorders. Omeprazole sulfone inhibits pancreatic cancer cell proliferation, induces apoptosis , autophagosome accumulation (elevated LC3-I and LC3-II levels), oxidative stress, and cytogenetic imbalance, modulates lysosomal transport, reduces inflammatory cytokines. Omeprazole sulfone alters small intestinal morphology and magnesium absorption, and induces gastric mucosa morphologic changes. Omeprazole sulfone aslo has neuroprotective and antibacterial effects.

Application

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Product Information

• Catalog No.: HY-B0113S2
• CAS No.: 1189891-71-1
• Molecular Formula: C17H16D3N3O4S
• Molecular Weight: 364.43
• Purity: 99.0%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source