GSK-690693 (Standard)

Overview

GSK-690693 (Standard) is the analytical standard of GSK-690693 ( HY-10249 ). This product is intended for research and analytical applications. GSK-690693 is an ATP-competitive pan-Akt inhibitor with IC 50 s of 2 nM, 13 nM, 9 nM for Akt1 , Akt2 and Akt3 , respectively. GSK-690693 is also an AMPK inhibitor , affects Unc-51-like autophagy activating kinase 1 ( ULK1 ) activity and robustly inhibits STING-dependent IRF3 activation.

Application

Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Autophagy | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > Akt | Products > Signaling Pathways > AMPK | Products > Signaling Pathways > Autophagy

Product Information

• Catalog No.: HY-10249R
• CAS No.: 937174-76-0
• Molecular Formula: C21H27N7O3
• Molecular Weight: 425.48
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source