Pefloxacin

Overview

Pefloxacin (Pefloxacinium) is a broad spectrum antibiotic . Pefloxacin blocks DNA replication by inhibiting DNA gyrase . Pefloxacin inhibits DNA relaxation catalyzed by topoisomerase I with an IC 50 of 45 μg/mL. Pefloxacin exhibits antibacterial activity against Escherichia coli , Pseudomonas aeruginosa , and Bacteroides fragilis with MIC 90 s of 0.12, 4, and 16 mg/L, respectively. Pefloxacin has anti- Plasmodium yoelii infection activity. Pefloxacin increase UVA-induced edema and immunesuppression. Pefloxacin can be used for infection studies.

Application

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Product Information

• Catalog No.: HY-B0147
• CAS No.: 70458-92-3
• Molecular Formula: C17H20FN3O3
• Molecular Weight: 333.36
• Purity: 99.37%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 0.1 mg/mL (0.30 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source