Pefloxacin-d 5

Overview

Pefloxacin -d 5 (Pefloxacinium-d 5 ) is the deuterium labeled Pefloxacin ( HY-B0147 ). Pefloxacin (Pefloxacinium) is a broad spectrum antibiotic . Pefloxacin blocks DNA replication by inhibiting DNA gyrase . Pefloxacin inhibits DNA relaxation catalyzed by topoisomerase I with an IC 50 of 45 μg/mL. Pefloxacin exhibits antibacterial activity against Escherichia coli , Pseudomonas aeruginosa , and Bacteroides fragilis with MIC 90 s of 0.12, 4, and 16 mg/L, respectively. Pefloxacin has anti- Plasmodium yoelii infection activity. Pefloxacin increase UVA-induced edema and immunesuppression. Pefloxacin can be used for infection studies.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Others | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Infection | Products > Signaling Pathways > Bacterial | Products > Signaling Pathways > Isotope-Labeled Compounds | Products > Signaling Pathways > Antibiotic | Products > Signaling Pathways > DNA/RNA Synthesis | Products > Signaling Pathways > Parasite | Products > Signaling Pathways > Topoisomerase

Product Information

• Catalog No.: HY-B0147S
• CAS No.: 1228182-51-1
• Molecular Formula: C17H15D5FN3O3
• Molecular Weight: 338.39
• Purity: 98.33%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source