Mizolastine dihydrochloride is an orally active, high affinity and specific peripheral histamine H1 receptor antagonist (second generation antihistamine). Mizolastine dihydrochloride effectively inhibits mRNA expression of VEGF165 , VEGF120 , TNF-α and KC . Mizolastine dihydrochloride can be used in studies of allergic rhinitis and chronic idiopathic urticarial.
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